Physics of Fluids - Publications

Blood Flow Quantification with High-Frame-Rate Contrast-Enhanced Ultrasound Velocimetry in Stented Aortoiliac Arteries: In Vivo Feasibility

Open Access
Ultrasound in Medicine and Biology 48, 1518–1527 (2022)

Authors

	Stefan Engelhard
	Majorie van Helvert
	Jason Voorneveld
	Johan G. Bosch
	Guillaume Lajoinie
	Erik Groot Jebbink
	Michel Versluis

BibTeΧ

@article{ENGELHARD20221518,
title = {Blood Flow Quantification with High-Frame-Rate, Contrast-Enhanced Ultrasound Velocimetry in Stented Aortoiliac Arteries: In Vivo Feasibility},
journal = {Ultrasound in Medicine & Biology},
volume = {48},
number = {8},
pages = {1518-1527},
year = {2022},
issn = {0301-5629},
doi = {https://doi.org/10.1016/j.ultrasmedbio.2022.03.016},
url = {https://www.sciencedirect.com/science/article/pii/S0301562922001235},
author = {Stefan Engelhard and Majorie {van Helvert} and Jason Voorneveld and Johan G. Bosch and Guillaume Lajoinie and Erik Groot Jebbink and Michel M.P.J. Reijnen and Michel Versluis},
keywords = {High frame rate, Contrast-enhanced ultrasound, Particle image velocimetry, Aortoiliac occlusive disease, Arterial stenting, Endovascular treatment},
abstract = {Local flow patterns influence stent patency, while blood flow quantification in stents is challenging. The aim of this study was to investigate the feasibility of 2-D blood flow quantification using high-frame-rate, contrast-enhanced ultrasound (HFR-CEUS) and particle image velocimetry (PIV), or echoPIV, in patients with aortoiliac stents. HFR-CEUS measurements were performed at 129 locations in 62 patients. Two-dimensional blood flow velocity fields were obtained using echoPIV. Visual inspection was performed by five observers to evaluate feasibility. The contrast-to-background ratio and average vector correlation were calculated and compared between stented and native vessel segments. Flow quantification with echoPIV was feasible in 128 of 129 locations (99%), with optimal quantification in 40 of 129 locations (31%). Partial quantification was achieved in 88 of 129 locations (68%), where one or multiple limiting issues occurred (not related to the stent) including loss of correlation during systole (57/129), short vessel segments (20/129), loss of contrast during diastole (20/129) and shadow regions (20/129). The contrast-to-background ratio and vector correlation were lower downstream in the imaged blood vessel, independent of the location of the stent. In conclusion, echoPIV was feasible in stents placed in the aortoiliac region, and the stents did not adversely affect flow tracking.}
}